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When ketoprofen for external use is used in women at the late stage of pregnancy, it may cause fetal ductus arteriosus systole. Therefore, do not use this product in women at the late stage of pregnancy.
The safety of this product during pregnancy (other than women at the late stage of pregnancy), delivery or lactation has not been established. Therefore, this product should be used only when the therapeutic benefit for these patients is considered to outweigh the risk.
When ketoprofen for external use was used at the mid stage of pregnancy, oligohydramnios was reported. Therefore, keep the use of this product to a minimum and use with caution.
40 mg: It has been reported that the use of cyclooxygenase inhibitors (oral preparations, suppositories) in pregnant women caused foetal renal impairment, urine output decreased and subsequent oligohydramnios.
